Source: eigensoft Maintainer: Debian Med Packaging Team Uploaders: Steffen Moeller , Andreas Tille Section: science Priority: optional Build-Depends: debhelper-compat (= 13), gfortran, libblas-dev, liblapack-dev, liblapacke-dev, libgsl-dev Standards-Version: 4.5.0 Vcs-Browser: https://salsa.debian.org/med-team/eigensoft Vcs-Git: https://salsa.debian.org/med-team/eigensoft.git Homepage: http://www.hsph.harvard.edu/faculty/alkes-price/software/ Rules-Requires-Root: no Package: eigensoft Architecture: any Depends: ${shlibs:Depends}, ${misc:Depends}, ${perl:Depends} Recommends: gnuplot Description: reduction of population bias for genetic analyses The EIGENSOFT package combines functionality from the group's population genetics methods (Patterson et al. 2006) and their EIGENSTRAT stratification method (Price et al. 2006). The EIGENSTRAT method uses principal components analysis to explicitly model ancestry differences between cases and controls along continuous axes of variation; the resulting correction is specific to a candidate marker's variation in frequency across ancestral populations, minimizing spurious associations while maximizing power to detect true associations. The EIGENSOFT package has a built-in plotting script and supports multiple file formats and quantitative phenotypes.