Source: hhsuite Maintainer: Debian Med Packaging Team Uploaders: Laszlo Kajan , Andreas Tille , Sascha Steinbiss Section: science Priority: optional Build-Depends: debhelper (>= 11~), libffindex0-dev (>= 0.9.9.8), cmake, texlive-latex-base, texlive-latex-recommended, imagemagick, help2man Standards-Version: 4.3.0 Vcs-Browser: https://salsa.debian.org/med-team/hhsuite Vcs-Git: https://salsa.debian.org/med-team/hhsuite.git Homepage: https://toolkit.tuebingen.mpg.de/ Package: hhsuite Architecture: amd64 Depends: ${shlibs:Depends}, ${misc:Depends}, ffindex (>= 0.9.9.8), hhsuite-data (= ${source:Version}), python Breaks: hhsuite-data (<= 2.0.16-1) Description: sensitive protein sequence searching based on HMM-HMM alignment HH-suite is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). . This package contains HHsearch and HHblits among other programs and utilities. . HHsearch takes as input a multiple sequence alignment (MSA) or profile HMM and searches a database of HMMs (e.g. PDB, Pfam, or InterPro) for homologous proteins. HHsearch is often used for protein structure prediction to detect homologous templates and to build highly accurate query-template pairwise alignments for homology modeling. . HHblits can build high-quality MSAs starting from single sequences or from MSAs. It transforms these into a query HMM and, using an iterative search strategy, adds significantly similar sequences from the previous search to the updated query HMM for the next search iteration. Compared to PSI-BLAST, HHblits is faster, up to twice as sensitive and produces more accurate alignments. Package: hhsuite-doc Architecture: all Section: doc Depends: ${shlibs:Depends}, ${misc:Depends} Recommends: hhsuite Breaks: hhsuite (<= 2.0.16-1) Replaces: hhsuite (<= 2.0.16-1) Description: documentation for HHsuite for HMM-HMM comparisons HH-suite is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). . This package provides a PDF with the user guide for HH-suite. Package: hhsuite-data Architecture: all Depends: ${misc:Depends} Description: sensitive protein sequence searching based on HMM-HMM alignment (data) HH-suite is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). . This package contains architecture independent scripts and data files.