Source: hhsuite Maintainer: Debian Med Packaging Team Uploaders: Laszlo Kajan , Andreas Tille , Sascha Steinbiss Section: science Priority: optional Build-Depends: debhelper-compat (= 13), libsimde-dev, cmake, imagemagick, help2man Standards-Version: 4.6.1 Vcs-Browser: https://salsa.debian.org/med-team/hhsuite Vcs-Git: https://salsa.debian.org/med-team/hhsuite.git Homepage: https://toolkit.tuebingen.mpg.de/ Rules-Requires-Root: no Package: hhsuite Architecture: any Depends: ${shlibs:Depends}, ${misc:Depends}, ${perl:Depends}, hhsuite-data (= ${source:Version}), python3 Conflicts: ffindex Built-Using: ${simde:Built-Using} Description: sensitive protein sequence searching based on HMM-HMM alignment HH-suite is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). . This package contains HHsearch and HHblits among other programs and utilities. . HHsearch takes as input a multiple sequence alignment (MSA) or profile HMM and searches a database of HMMs (e.g. PDB, Pfam, or InterPro) for homologous proteins. HHsearch is often used for protein structure prediction to detect homologous templates and to build highly accurate query-template pairwise alignments for homology modeling. . HHblits can build high-quality MSAs starting from single sequences or from MSAs. It transforms these into a query HMM and, using an iterative search strategy, adds significantly similar sequences from the previous search to the updated query HMM for the next search iteration. Compared to PSI-BLAST, HHblits is faster, up to twice as sensitive and produces more accurate alignments. Package: hhsuite-data Architecture: all Multi-Arch: foreign Depends: ${misc:Depends} Description: sensitive protein sequence searching based on HMM-HMM alignment (data) HH-suite is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). . This package contains architecture independent scripts and data files.