Source: indelible Maintainer: Debian Med Packaging Team Uploaders: Fabian Klötzl , Étienne Mollier Section: science Priority: optional Build-Depends: debhelper-compat (= 13) Standards-Version: 4.6.2 Vcs-Browser: https://salsa.debian.org/med-team/indelible Vcs-Git: https://salsa.debian.org/med-team/indelible.git Homepage: http://abacus.gene.ucl.ac.uk/software/indelible/ Rules-Requires-Root: no Package: indelible Architecture: any Depends: ${shlibs:Depends}, ${misc:Depends} Description: powerful and flexible simulator of biological evolution INDELible is a new, portable, and flexible application for biological sequence simulation that combines many features in the same place for the first time. Using a length-dependent model of indel formation it can simulate evolution of multi-partitioned nucleotide, amino-acid, or codon data sets through the processes of insertion, deletion, and substitution in continuous time. . Nucleotide simulations may use the general unrestricted model or the general time reversible model and its derivatives, and amino-acid simulations can be conducted using fifteen different empirical rate matrices. Substitution rate heterogeneity can be modeled via the continuous and discrete gamma distributions, with or without a proportion of invariant sites. INDELible can also simulate under non-homogeneous and non-stationary conditions where evolutionary models are permitted to change across a phylogeny. . Unique among indel simulation programs, INDELible offers the ability to simulate using codon models that exhibit nonsynonymous/synonymous rate ratio heterogeneity among sites and/or lineages.