Source: provean Section: science Priority: optional Maintainer: Debian Med Packaging Team Uploaders: Andrius Merkys , Build-Depends: cd-hit, debhelper-compat (= 13), ncbi-blast+, Standards-Version: 4.6.1 Homepage: http://provean.jcvi.org Vcs-Browser: https://salsa.debian.org/med-team/provean Vcs-Git: https://salsa.debian.org/med-team/provean.git Rules-Requires-Root: no Package: provean Architecture: any Depends: ${misc:Depends}, ${shlibs:Depends}, Description: Protein Variation Effect Analyzer PROVEAN (Protein Variation Effect Analyzer) is a software tool which predicts whether an amino acid substitution or indel has an impact on the biological function of a protein. . PROVEAN is useful for filtering sequence variants to identify nonsynonymous or indel variants that are predicted to be functionally important. . The performance of PROVEAN is comparable to popular tools such as SIFT or PolyPhen-2. . A fast computation approach to obtain pairwise sequence alignment scores enabled the generation of precomputed PROVEAN predictions for 20 single AA substitutions and a single AA deletion at every amino acid position of all protein sequences in human and mouse.