Source: python-mhcseqs Section: science Maintainer: Debian Med Packaging Team Uploaders: Steffen Moeller Build-Depends: debhelper-compat (= 14), dh-sequence-python3, pybuild-plugin-pyproject, python3-all, python3-mhcgnomes (>= 3.41.0) , python3-pytest , python3-setuptools, Standards-Version: 4.7.4 Testsuite: autopkgtest-pkg-pybuild Homepage: https://github.com/pirl-unc/mhcseqs Vcs-Browser: https://salsa.debian.org/med-team/python-mhcseqs Vcs-Git: https://salsa.debian.org/med-team/python-mhcseqs.git Package: python3-mhcseqs Section: python Architecture: all Depends: ${python3:Depends}, python3-mhcgnomes (>= 3.41.0), Description: Python library for MHC protein sequence curation The major histocompatibility complex (MHC) encodes cell-surface proteins that present peptide antigens to T cells. In humans these proteins are called human leukocyte antigens (HLA). Class I proteins are expressed on nearly all nucleated cells and primarily present intracellular peptides; class II proteins are mainly expressed by professional antigen-presenting cells and primarily present peptides derived from extracellular proteins. . mhcseqs downloads and curates MHC protein sequences from IMGT/HLA and IPD-MHC, supplements them with selected UniProt and GenBank records, and decomposes class I and class II proteins into their binding-groove and supporting domains. It can handle full-length proteins, signal-peptide-stripped deposits, and common sequence fragments. . This package provides the Python 3 library and bundled reference data. Package: mhcseqs Architecture: all Depends: ${python3:Depends}, python3-mhcseqs (= ${binary:Version}), Description: MHC protein sequence curation and binding-groove extraction The major histocompatibility complex (MHC) encodes cell-surface proteins that present peptide antigens to T cells. In humans these proteins are called human leukocyte antigens (HLA). Class I proteins are expressed on nearly all nucleated cells and primarily present intracellular peptides; class II proteins are mainly expressed by professional antigen-presenting cells and primarily present peptides derived from extracellular proteins. . mhcseqs downloads and curates MHC protein sequences from IMGT/HLA and IPD-MHC, supplements them with selected UniProt and GenBank records, and decomposes class I and class II proteins into their binding-groove and supporting domains. It can handle full-length proteins, signal-peptide-stripped deposits, and common sequence fragments. . This package provides the mhcseqs command-line program.