Source: python-varcode Standards-Version: 4.7.4 Maintainer: Debian Med Packaging Team Uploaders: Steffen Moeller , Section: science Testsuite: autopkgtest-pkg-pybuild Build-Depends: debhelper-compat (= 14), dh-sequence-python3, pybuild-plugin-pyproject, pyensembl , python3-all, python3-memoized-property , python3-numpy , python3-pandas , python3-pysam , python3-pytest , python3-sercol (>= 1.0.3) , python3-serializable (>= 1.1.0) , python3-setuptools, python3-typechecks , Vcs-Browser: https://salsa.debian.org/med-team/python-varcode Vcs-Git: https://salsa.debian.org/med-team/python-varcode.git Homepage: https://github.com/openvax/varcode Package: python3-varcode Architecture: all Section: python Depends: python3-sercol (>= 1.0.3), python3-serializable (>= 1.1.0), python3-typechecks, ${python3:Depends}, Recommends: varcode (= ${source:Version}), Suggests: python3-pysam, Description: genomic variant effect prediction library for Python 3 Varcode predicts how genomic variants affect genes, transcripts and proteins using Ensembl annotations. It handles single-nucleotide variants, insertions, deletions, multi-nucleotide substitutions and structural variants, and models their coding, splicing and protein-sequence consequences. . This package provides the Python 3 module. The command-line programs are available in the varcode package. Package: varcode Architecture: all Depends: python3-varcode (= ${source:Version}), ${python3:Depends}, Description: command-line genomic variant effect prediction tools This package provides command-line interfaces to the Varcode library. The varcode command reads variants from VCF, MAF and JSON files, or accepts genomic coordinates directly, then reports overlapping genes and predicted effects on transcripts and protein sequences. . The varcode-genes command reports overlapping genes. The "varcode check-samples" command compares pairs of VCF samples by germline genotype concordance and shared somatic variants to flag possible sample mix-ups.