Source: r-bioc-pfamanalyzer Standards-Version: 4.7.3 Maintainer: Debian R Packages Maintainers Uploaders: Andreas Tille , Section: gnu-r Testsuite: autopkgtest-pkg-r Build-Depends: debhelper-compat (= 13), dh-r, r-base-dev, r-cran-readr, r-cran-stringr, r-cran-dplyr, r-cran-tibble, r-cran-magrittr, architecture-is-64-bit, architecture-is-little-endian, Vcs-Browser: https://salsa.debian.org/r-pkg-team/r-bioc-pfamanalyzer Vcs-Git: https://salsa.debian.org/r-pkg-team/r-bioc-pfamanalyzer.git Homepage: https://bioconductor.org/packages/pfamAnalyzeR/ Rules-Requires-Root: no Package: r-bioc-pfamanalyzer Architecture: all Depends: ${R:Depends}, ${misc:Depends}, Recommends: ${R:Recommends}, Suggests: ${R:Suggests}, Description: GNU R identification of domain isotypes in pfam data Protein domains is one of the most import annoation of proteins that are with the Pfam database/tool being (by far) the most used tool. This R package enables the user to read the pfam prediction from both webserver and stand-alone runs into R. It was recently shown most human protein domains exist as multiple distinct variants termed domain isotypes. Different domain isotypes are used in a cell, tissue, and disease- specific manner. Accordingly, it was found that domain isotypes, compared to each other, modulate, or abolish the functionality of a protein domain. This R package enables the identification and classification of such domain isotypes from Pfam data.