Source: r-cran-spp Maintainer: Debian R Packages Maintainers Uploaders: Andreas Tille Section: gnu-r Testsuite: autopkgtest-pkg-r Priority: optional Build-Depends: debhelper-compat (= 13), dh-r, r-base-dev, r-cran-rcpp, r-bioc-rsamtools, r-cran-catools, r-cran-bh Standards-Version: 4.5.0 Vcs-Browser: https://salsa.debian.org/r-pkg-team/r-cran-spp Vcs-Git: https://salsa.debian.org/r-pkg-team/r-cran-spp.git Homepage: https://cran.r-project.org/package=spp Rules-Requires-Root: no Package: r-cran-spp Architecture: any Depends: ${R:Depends}, ${shlibs:Depends}, ${misc:Depends} Recommends: ${R:Recommends} Suggests: ${R:Suggests} Conflicts: r-other-hms-dbmi-spp Provides: r-other-hms-dbmi-spp Replaces: r-other-hms-dbmi-spp Description: GNU R ChIP-seq processing pipeline R package for anlaysis of ChIP-seq and other functional sequencing data * Assess overall DNA-binding signals in the data and select appropriate quality of tag alignment. * Discard or restrict positions with abnormally high number of tags. * Calculate genome-wide profiles of smoothed tag density and save them in WIG files for viewing in other browsers. * Calculate genome-wide profiles providing conservative statistical estimates of fold enrichment ratios along the genome. These can be exported for browser viewing, or thresholded to determine regions of significant enrichment/depletion. * Determine statistically significant point binding positions * Assess whether the set of point binding positions detected at a current sequencing depth meets saturation criteria, and if does not, estimate what sequencing depth would be required to do so.