Source: thesias Maintainer: Debian Med Packaging Team Uploaders: Dylan Aïssi Section: science Priority: optional Build-Depends: debhelper-compat (= 12), default-jdk Standards-Version: 4.4.1 Vcs-Browser: https://salsa.debian.org/med-team/thesias Vcs-Git: https://salsa.debian.org/med-team/thesias.git Homepage: https://github.com/daissi/thesias Package: thesias Architecture: any Depends: ${misc:Depends}, ${shlibs:Depends}, default-jre Description: Testing Haplotype Effects In Association Studies The objectif of the THESIAS program is to performed haplotype-based association analysis in unrelated individuals. This program is based on the maximum likelihood model described in Tregouet et al. 2002 (Hum Mol Genet 2002,11: 2015-2023) and is linked to the SEM algorithm (Tregouet et al. Ann Hum Genet 2004,68: 165-177). THESIAS allows one to simultaneous estimate haplotype frequencies and their associate effects on the phenotype of interest. In this new THESIAS release, quantitative, qualitative (logistic and matched-pair analysis), categorical and survival outcomes can be studied. X-linked haplotype analysis is also feasible. Covariate-adjusted haplotype effects as well as haplotype x covariate interactions can also be investigated.