Version 44.1.1-1.2 of python-setuptools is marked for autoremoval from testing on Mon 28 Nov 2022. It is affected by #938168. The removal of python-setuptools will also cause the removal of (transitive) reverse dependency: python-ipaddress. It depends (transitively) on pypy, affected by #1011926.
You should try to prevent the removal by fixing these RC bugs.